Morphological differentiation of nerve fibers: central, peripheral, myelinated and unmyelinated.

نویسندگان

  • J Goto
  • N Goto
  • H Ezure
  • N Nonaka
  • X Ma
چکیده

We have developed a new technique for the morphological differentiation of various nerve fibers which is especially suitable for the morphometric study of nerve fibers of the human nervous system with the help of an image-analyzer. The knowledge from findings by this technique, which is based on several study methods, may be of importance in promoting further neuromorphologic studies and in properly understanding various aspects of neurological symptomatology and the aging process of the nervous system including nerve fibers.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Ultrastructural and Morphometric Analysis of Peripheral Nerve Regeneration Within Silicone Tubes

203 Abstract: Semi-thin and thin sections were used to observe the morphogenesis of peripheral nerves regenerating in silicone tubes. The progress of peripheral nerve regeneration across a 10 mm gap within the silicone tubes was examined after 3, 6 and 9 months. The left sciatic nerves of rats were transected. The proximal and distal nerve stumps were inserted into a silicone tube, in which the...

متن کامل

An isoform of ankyrin is localized at nodes of Ranvier in myelinated axons of central and peripheral nerves

Two variants of ankyrin have been distinguished in rat brain tissue using antibodies: a broadly distributed isoform (ankyrinB) that represents the major form of ankyrin in brain and another isoform with a restricted distribution (ankyrinR) that shares epitopes with erythrocyte ankyrin. The ankyrinR isoform was localized by immunofluorescence in cryosections of rat spinal cord gray matter and my...

متن کامل

Effects of 4-methylcatechol on skin reinnervation: promotion of cutaneous nerve regeneration after crush injury.

We assessed the effects of treatment with 4-methylcatechol (4MC), a known inducer of nerve growth factor, on peripheral nerve regeneration by analyzing cutaneous and muscular reinnervation in mice after sciatic nerve crush injury. At 3 months postinjury, the skin innervation index was significantly higher in the 4MC group than the control group (p=0.0002); there was also increased unmyelinated ...

متن کامل

Schwann cell glycogen selectively supports myelinated axon function.

OBJECTIVE Interruption of energy supply to peripheral axons is a cause of axon loss. We determined whether glycogen was present in mammalian peripheral nerve, and whether it supported axon conduction during aglycemia. METHODS We used biochemical assay and electron microscopy to determine the presence of glycogen, and electrophysiology to monitor axon function. RESULTS Glycogen was present i...

متن کامل

Glial cell line-derived neurotrophic factor alters axon schwann cell units and promotes myelination in unmyelinated nerve fibers.

Glial cell line-derived neurotrophic factor (GDNF) plays an important role in the development and maintenance of a subset of dorsal root ganglion sensory neurons. We administered high-dose exogenous recombinant human GDNF (rhGDNF) daily to adult rats to examine its effect on unmyelinated axon-Schwann cell units in intact peripheral nerves. In rhGDNF-treated animals, there was a dramatic prolife...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Okajimas folia anatomica Japonica

دوره 77 6  شماره 

صفحات  -

تاریخ انتشار 2001